HGH Fragment 176-191 is a spliced variant of native human growth hormone. Specifically, it is made of the last 16 amino acids on GH’s long 191 amino acid sequence. This fragment seems to retain some (not all) of the biological activity of growth hormone. On the one hand, the compound is no longer able to bind with the cellular GH receptor. As such, it does not elevate serum IGF-1, nor appear to have anabolic effects. On the other, it may still have distinct lipolytic (fat loss) properties. A drug like this could be applicable in situations where fat loss is desired, but GH’s wider spectrum of anabolic effects (and potential side effects) is not. In the fitness community, this substance is used exclusively for fat loss.
HGH Fragment 176-191 is generally given via subcutaneous (SC) injection.
Frag 176-191, or human growth hormone (176-191) in research is primarily used as a replacement therapy for those dealing with growth hormone deficiencies. In its natural form, this peptide is created and comes from somatotropic cells that are located in the anterior pituitary gland. In its synthetic form, researchers have found that Frag 176-191 is able to aid in weight and fat control as well as improve an individual’s bone strength and muscle recovery.
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